Epigenomics

Learn about changes in expression

Services

ChIP-seq analysis

Identification and quantitative analysis of differential binding

DNA methylation

Discovery and annotation of promoters

HiC data analysis

Integration with Transcriptomics and Genomics data

Related Omics Tools

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Hi Cloud

Hi Cloud has dedicated his entire life in the cloud to processing and understanding Hi-C data.

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Code 0 and Greenc

Long non-coding RNAs (lncRNAs) are functional non-translated molecules longer than 200 nucleotides with diverse roles transcriptional regulation and conformational changes in proteins.

Code 0 is available at greenc.sequentiabiotech.com

Code 0 discovers, deciphers and annotates lncRNAs in any genome or transcriptome of interest, which are then stored in our GreenC database.

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What can you expect from us

Integrated project management: from experiment design to data interpretation

High data privacy and security

Curated output to quickly reach the scientific goal

Fast production of results

Private IT infrastructure and cloud systems

Custom workflows

Up-to-date scientific knowledge

A mixed approach of unique well-referenced and published bioinformatics methods

Research in recent years has shown that neither the sequence of the genes nor their expression can alone explain the complex workings of genomes. That is why the study of epigenetics has become a key factor for understanding biological processes.

At Sequentia, we have innovative analysis pipelines that combined with sequencing technologies enable us to study how transcription factors and histones interact with the chromatin (ChIP-Seq) and identify regulatory elements such as promoters or the distribution of DNA methylation. In this way, the distribution profiles of the proteins that bind DNA and the distribution of methylation in the genome can be plotted and we can see how they change depending on conditions or tissues (differential analysis).

We also use a pipeline of Chromosome Conformation Capture data through which the three-dimensional interactions of chromatin are identified and analysed, thus providing more information on the complex study of the rules that govern epigenomics.
Another strong point of our service is that by combining all of the methods we use, we can integrate data from separate research and create software solutions to independently preserve, display and integrate the analyses.

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