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What can you expect from us
The study of the set of genes of a genome is a fundamental step in understanding its biological processes and functions. This is now possible thanks to transcriptomics and the new sequencing technologies that allow us to know all of an organism’s genes in detail, in specific conditions and tissues.
At Sequentia, we have pipelines that integrate the latest bioinformatics processes in this field through which we quickly identify genes, transcripts and splicing variants, paying attention to their functions and organisation using molecular networks. Our pipelines are used in both model organisms and new species to which they can incorporate the transcriptome, even if there is no reference genome, or species with partial annotations (Reference Guided Transcriptome Assembly).
On the other hand, the development of new algorithms to reconstruct transcripts has enabled us to create specific pipelines to record and study types of RNA such as lncRNAs, sORFs and cRNAs, in addition to identifying genetic fusions.
By combining the methods we use, we can integrate data from separate research and create software solutions to independently preserve, display and integrate the analyses.
Authors: A. Borgognone, W. Sanseverino, R. Aiese Cigliano and R. [...]
Authors: V. Ruggieri, K. G. Alexiou, J. Morata, J. Argyris, [...]
Maize RNA PolIV affects the expression of genes with nearby TE insertions and has a genome-wide repressive impact on transcription
Authors: Forestan, C., Farinati, S., Cigliano, R. A., Lunardon, A., [...]