{"id":12395,"date":"2026-02-25T10:29:34","date_gmt":"2026-02-25T10:29:34","guid":{"rendered":"https:\/\/dev.sequentiabiotech.com\/?post_type=new-and-event&#038;p=12395"},"modified":"2026-03-18T15:03:56","modified_gmt":"2026-03-18T15:03:56","slug":"genomic-surveillance-of-foodborne-pathogens-the-new-standard-in-food-safety","status":"publish","type":"new-and-event","link":"https:\/\/www.sequentiabiotech.com\/it\/new-and-event\/genomic-surveillance-of-foodborne-pathogens-the-new-standard-in-food-safety\/","title":{"rendered":"Genomic Surveillance of Foodborne Pathogens: The New Standard in Food Safety"},"content":{"rendered":"<h2>Genomic Surveillance of Foodborne Pathogens: The New Standard in Food Safety<\/h2>\n<p><span style=\"font-weight: 400;\">In a globalized market, a single undetected outbreak can cost over $10 million and destroy decades of consumer trust. With the <\/span><b>European Food Safety Authority (EFSA)<\/b><span style=\"font-weight: 400;\"> transitioning to <\/span><b>Whole Genome Sequencing (WGS)<\/b><span style=\"font-weight: 400;\"> as the new indispensable standard for pathogen surveillance, food safety has shifted from a reactive approach to one of genomic precision. At Sequentia, we transform regulatory compliance into a strategic advantage through proactive, high-resolution surveillance.<\/span><\/p>\n<h2><b>The Industry Challenge: Managing Global Risk<\/b><\/h2>\n<p><b><\/b>The scale of the current food safety crisis is measured in both human and economic terms. According to the World Health Organization (WHO) Global Strategy 2022\u20132030, foodborne diseases remain a critical priority:<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Human Impact<\/b><span style=\"font-weight: 400;\">: Annually, an estimated 600 million people are affected by foodborne illnesses\u2014nearly 1 in 10 people globally.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Economic Magnitude<\/b><span style=\"font-weight: 400;\">: In low- and middle-income countries (LMICs), the annual impact related to medical costs and productivity is estimated at $110 billion.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Protecting Brand Equity<\/b><span style=\"font-weight: 400;\">: While the average direct cost of a recall can exceed $10 million, the long-term priority is maintaining consumer confidence; data shows that 21% of consumers may change their purchasing habits following a safety incident.<\/span><\/li>\n<\/ul>\n<h2><b>Common Pathogens &amp; Interaction Points<\/b><\/h2>\n<p><span style=\"font-weight: 400;\">Understanding how pathogens interact with various supply chains is the foundation of an effective prevention strategy. Our technology helps identify and monitor key organisms across different sectors:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Salmonella<\/b><span style=\"font-weight: 400;\">: Often monitored within poultry, egg, and fresh produce supply chains.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Listeria<\/b><span style=\"font-weight: 400;\">: A priority for the deli meat and soft cheese sectors in the EU and US due to its persistence.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Campylobacter<\/b><span style=\"font-weight: 400;\">: Frequently analyzed in raw poultry and dairy environments, particularly in the European Union.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>E. coli (STEC)<\/b><span style=\"font-weight: 400;\">: A key focus for ground beef and leafy green producers to ensure safety standards.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Norovirus<\/b><span style=\"font-weight: 400;\">: Closely tracked in ready-to-eat (RTE) foods and shellfish logistics.<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2><b>The Genomic Revolution: WGS vs. Traditional Methods<\/b><\/h2>\n<p>The traditional method (PFGE) is slow, low-resolution, and often misses small or diffuse outbreaks. Sequentia is driving the shift toward Whole Genome Sequencing (WGS):<\/p>\n<table>\n<tbody>\n<tr>\n<td><b>Feature<\/b><\/td>\n<td><b>The Old Way (PFGE)<\/b><\/td>\n<td><b>The New Way (WGS)<\/b><\/td>\n<\/tr>\n<tr>\n<td><b>Speed &amp; Precision<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Slow &amp; Low-resolution<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Fast &amp; Ultra-high precision<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Sensitivity<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Often misses small\/diffuse outbreaks<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Solves outbreaks with as few as 2 cases<\/span><\/td>\n<\/tr>\n<tr>\n<td><b>Approach<\/b><\/td>\n<td><span style=\"font-weight: 400;\">Reactive: Required epidemiological clues first<\/span><\/td>\n<td><span style=\"font-weight: 400;\">Proactive: Lab data detects outbreaks first<\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><b><br \/>\n<\/b><b>Outcome: <\/b><span style=\"font-weight: 400;\">By identifying precise genetic matches between isolates, WGS provides robust, defensible evidence to pinpoint contamination sources\u2014enabling faster recalls, targeted interventions, and the prevention of further illness.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h2><b>PROKY\u2122: Your Decision Engine for Genomic Surveillance<\/b><\/h2>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Comprehensive isolate profiling<\/b><span style=\"font-weight: 400;\">: A true &#8220;end-to-end&#8221; solution that manages everything from raw sequence quality control to full genomic characterization, including <\/span><i><span style=\"font-weight: 400;\">de novo<\/span><\/i><span style=\"font-weight: 400;\"> assembly, functional annotation, and high-resolution serotyping.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Comparative intelligence &amp; outbreak tracking<\/b><span style=\"font-weight: 400;\">: PROKY\u2122 aggregates data across multiple samples to visualize genetic lineages through high-quality phylogenetic trees and SNP distance matrices\u2014essential tools for confirming transmission chains during epidemic investigations.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Advanced risk &amp; virulence detection<\/b><span style=\"font-weight: 400;\">: The platform automatically scans for antimicrobial resistance (AMR) genes and virulence markers, including critical resistance to biocides and disinfectants, ensuring a holistic view of pathogen risk.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Genetic mobility analysis<\/b><span style=\"font-weight: 400;\">: By detecting plasmids and mobile genetic elements, PROKY\u2122 determines their association with resistance genes, providing a crucial understanding of how &#8220;superbugs&#8221; evolve and spread.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Regulatory &amp; compliance readiness<\/b><span style=\"font-weight: 400;\">:\u00a0 Built to exceed <\/span><b>ISO 13485<\/b><span style=\"font-weight: 400;\"> and <\/span><b>ISO 23418<\/b><span style=\"font-weight: 400;\"> standards, PROKY\u2122 ensures your laboratory is <\/span><b>future-proofed<\/b><span style=\"font-weight: 400;\"> against upcoming EFSA mandates for mandatory WGS analysis.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Proven economic impact<\/b>: Beyond enhancing safety, adopting real-time WGS surveillance through PROKY\u2122 is a sound financial investment; research indicates a <b>3-fold return on investment (ROI)<\/b> for institutions by averting costs associated with uncontained outbreaks.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h2>Resources &amp; References<b><\/b><\/h2>\n<ul>\n<li style=\"list-style-type: none;\">\n<ul>\n<li><a href=\"https:\/\/www.efsa.europa.eu\/en\/corporate-pubs\/efsa-strategy-2027-science-safe-food-sustainability\"><b>\u00a0EFSA Strategy 2022\u20132027: Science, Safe Food, Sustainability.<\/b><\/a> Explore the European framework moving towards the mandatory implementation of WGS for foodborne pathogen surveillance in the EU.<\/li>\n<li><a href=\"https:\/\/www.who.int\/publications\/i\/item\/9789240057685\"><b>WHO Global Strategy for Food Safety 2022\u20132030. <\/b><\/a>A strategic framework for strengthening national food safety systems and promoting global cooperation.<\/li>\n<li><a href=\"https:\/\/www.fao.org\/3\/i6582e\/i6582e.pdf\"><b>FAO: The impact of WGS on Food Safety Management<\/b><\/a><b>. <\/b>Detailed technical insights on the application of Whole Genome Sequencing for high-resolution pathogen surveillance.<\/li>\n<li aria-level=\"1\"><a href=\"https:\/\/doi.org\/10.1101\/2024.09.19.24313985\"><b>NIH: Impact of Real-Time Genomic Surveillance on Infection Prevention<\/b><\/a><b>. <\/b>Evidence-based study demonstrating the clinical and economic benefits of WGS in preventing healthcare-associated infections.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n","protected":false},"featured_media":12733,"parent":0,"template":"","meta":{"_acf_changed":false},"area-of-interest":[18],"news-events-category":[305],"omic":[29],"content-type":[33],"class_list":["post-12395","new-and-event","type-new-and-event","status-publish","has-post-thumbnail","hentry","area-of-interest-public-health-epidemiology","news-events-category-proky","omic-genomics","content-type-blog"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Genomic Surveillance of Foodborne Pathogens for Food Safety<\/title>\n<meta name=\"description\" content=\"Learn how genomic surveillance of foodborne pathogens using WGS is the new standard for food safety. 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