{"id":8935,"date":"2021-12-01T10:17:48","date_gmt":"2021-12-01T10:17:48","guid":{"rendered":"https:\/\/dev.sequentiabiotech.com\/publication\/prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process\/"},"modified":"2026-02-11T13:18:42","modified_gmt":"2026-02-11T13:18:42","slug":"prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process","status":"publish","type":"publication","link":"https:\/\/www.sequentiabiotech.com\/it\/publication\/prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process\/","title":{"rendered":"PRGdb 4.0: an updated database dedicated to genes involved in plant disease resistance process"},"content":{"rendered":"<p><strong>Authors:<\/strong> <span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Joan Calle\u00a0Garc\u00eda<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Anna Guadagno<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Andreu Paytuvi-Gallart<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Alfonso Saera-Vila<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Ciro\u00a0Gianmaria Amoroso<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Daniela D\u2019Esposito<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Giuseppe Andolfo<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Riccardo Aiese\u00a0Cigliano<\/a><span class=\"delimiter\">,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Walter Sanseverino<\/a><span class=\"delimiter\"><i class=\"icon-general-mail\"><\/i>,<\/span><\/span>\u00a0<span class=\"al-author-name-more js-flyout-wrap\"><a class=\"linked-name js-linked-name-trigger\">Maria\u00a0Raffaella Ercolano<\/a><\/span><\/p>\n<p><strong>Institutions:\u00a0<\/strong><\/p>\n<ul>\n<li>Sequentia Biotech, Barcelona, Spain<\/li>\n<li>\n<div class=\"institution\">Dipartimento di Agraria, Universit\u00e0 di Napoli \u2018Federico II\u2019, Via Universit\u00e0 100,\u00a080055 Portici,\u00a0Italy<\/div>\n<\/li>\n<\/ul>\n<p><strong>Publication: <\/strong>Nucleic Acids Research<\/p>\n<p><strong>Date:<\/strong> November 2021<\/p>\n<p><strong>Full paper:<\/strong> <a href=\"https:\/\/academic.oup.com\/nar\/article\/50\/D1\/D1483\/6438004?login=false\">PRGdb 4.0: an updated database dedicated to genes involved in plant disease resistance process<\/a><\/p>\n<p><strong>Abstract:<\/strong><\/p>\n<p>The Plant Resistance Genes database (PRGdb;\u00a0<a class=\"link link-uri openInAnotherWindow\" href=\"http:\/\/prgdb.org\/prgdb4\/\" target=\"_blank\" rel=\"noopener\">http:\/\/prgdb.org\/prgdb4\/<\/a>) has been greatly expanded, keeping pace with the increasing amount of available knowledge and data (sequenced proteomes, cloned genes, public analysis data, etc.). The easy-to-use style of the database website has been maintained, while an updated prediction tool, more data and a new section have been added. This new section will contain plant resistance transcriptomic experiments, providing additional easy-to-access experimental information. DRAGO3, the tool for automatic annotation and prediction of plant resistance genes behind PRGdb, has been improved in both accuracy and sensitivity, leading to more reliable predictions. PRGdb offers 199 reference resistance genes and 586.652 putative resistance genes from 182 sequenced proteomes. Compared to the previous release, PRGdb 4.0 has increased the number of reference resistance genes from 153 to 199, the number of putative resistance genes from 177K from 76 proteomes to 586K from 182 sequenced proteomes. A new section has been created that collects plant-pathogen transcriptomic data for five species of agricultural interest. Thereby, with these improvements and data expansions, PRGdb 4.0 aims to serve as a reference to the plant scientific community and breeders worldwide, helping to further study plant resistance mechanisms that contribute to fighting pathogens.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"featured_media":9493,"parent":0,"template":"","meta":{"_acf_changed":false},"omics-area":[38,40],"application-field":[34],"solution":[46],"publication-type":[49],"class_list":["post-8935","publication","type-publication","status-publish","has-post-thumbnail","hentry","omics-area-genomics","omics-area-transcriptomics","application-field-agritech","solution-air","publication-type-peer-reviewed-articles"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>PRGdb 4.0: an updated database dedicated to genes involved in plant disease resistance process - Sequentia<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sequentiabiotech.com\/it\/publication\/prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PRGdb 4.0: an updated database dedicated to genes involved in plant disease resistance process - Sequentia\" \/>\n<meta property=\"og:description\" content=\"Authors: Joan Calle\u00a0Garc\u00eda,\u00a0Anna Guadagno,\u00a0Andreu Paytuvi-Gallart,\u00a0Alfonso Saera-Vila,\u00a0Ciro\u00a0Gianmaria Amoroso,\u00a0Daniela D\u2019Esposito,\u00a0Giuseppe Andolfo,\u00a0Riccardo Aiese\u00a0Cigliano,\u00a0Walter Sanseverino,\u00a0Maria\u00a0Raffaella Ercolano Institutions:\u00a0 Sequentia Biotech, Barcelona, Spain Dipartimento di Agraria, Universit\u00e0 di Napoli \u2018Federico II\u2019, Via Universit\u00e0 100,\u00a080055 Portici,\u00a0Italy Publication: Nucleic Acids Research Date: November 2021 Full paper: PRGdb 4.0: an updated database dedicated to genes involved in plant disease resistance process Abstract: The Plant [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.sequentiabiotech.com\/it\/publication\/prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process\/\" \/>\n<meta property=\"og:site_name\" content=\"Sequentia\" \/>\n<meta property=\"article:modified_time\" content=\"2026-02-11T13:18:42+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.sequentiabiotech.com\/wp-content\/uploads\/2025\/06\/42-e1770713889474.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1080\" \/>\n\t<meta property=\"og:image:height\" content=\"524\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minuti\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.sequentiabiotech.com\\\/it\\\/publication\\\/prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process\\\/\",\"url\":\"https:\\\/\\\/www.sequentiabiotech.com\\\/it\\\/publication\\\/prgdb-4-0-an-updated-database-dedicated-to-genes-involved-in-plant-disease-resistance-process\\\/\",\"name\":\"PRGdb 4.0: an updated database dedicated to genes involved in plant disease resistance process - 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